The 23.6 x 15.6 mm or APS-C is not one I favor for photographing people. I can't have the perspective I want and the background blurring I want in one photograph. I'm not talking about DoF here but background blurring. They are not one and the same. The D800 gave me back my 105/2.5 AIS.
I would not be considering the either the Nikon D500 or Fuji XT2 for photographing people.
My experience with Fuji mostly is with their X100s fixed-lens camera; I have not used their ILC system except for occasionally trying it briefly.
Check out photos made with the 56mm f/1.2 APD (the latter part is important); e.g. there is a flickr group where you can find some examples. I think it looks quite nice in terms of out of focus rendering. I realize that light is lost due to the apodisation element and autofocus is limited to contrast detect but to me the results seem very nice.
Fuji also have 16/1.4, 23/1.4 etc. so there are plenty of fast wide angles, though not quite the equivalent of 24/1.4 on 35mm full frame.
Other advantages pertinent to photographing people is that you can take photos silently if you need/want to. I don't know what disadvantages there are (rolling shutter? maybe additional delay?) but for some situations this would be invaluable.
While the X-T2 has nice eyepoint and EVF, and indeed I can see the whole viewfinder image with glasses on, with the X-Pro2 I wasn't able to comfortably see the whole viewfinder image (neither optical nor EVF). If they improved the optical viewfinder by increasing its eyepoint and reduced the distortion, I would be very interested in this camera. Mostly for situations requiring that the camera be quieter than my DSLRs, and also to use the 56mm APD lens. I liked the OVF on the X100s but missed a convenient way of moving the focus point (the buttons are so small, and one has to first initiate AF point selection then move it and finish; with Nikons I just use the multi selector or thumbstick without having to go to a "focus point selection mode"). I understand this is now easier with the newest Fuji models.
However, I also disliked the way high ISO images were smeared by the X100s, the people looked a bit like wax models and there didn't seem to be a way to avoid it as far as I could see. This lead me to sell the X100s after half a year's use. At mid ISO the image quality was fine and I liked the quietness and lack of reaction from people when shooting street.
I would like to give the X-Pro2 a try, but I'm unconvinced by its viewfinder, and so I wait. Leica M would be another quiet option with optical viewfinder but it's out of my price range (with the fast lenses I would want to go with it). For now, for quietness I turn on Qc in my Nikon D5 or use the D810 (which is a bit slower and quieter) and hope that it's quiet enough. Usually it is. The high fps feature of the D5 is very loud though, but the remarkable autofocus performance makes it the appropriate tool for some situations. The D500 is much quieter than the D5 and of course the Fuji X-T2 is, as there is no mirror movement sound. Still, I stick to my Nikons as I prefer their viewfinders and work around the sound noise by trying to time shots carefully and use Qc on the D5 when appropriate. If I were to use the D500, I don't think I'd have much issue in terms of the sound from the camera, but I tend to go with the larger viewfinder and better image quality of FX in low light. Still, the camera sound noise is a consideration for me and maybe at some point I will buy a Fuji for silent shooting situations. Sony also have that capability but there is no optical viewfinder available.