So ignoring the body, can you expand on what the target or constraints of your shooting are.
Obviously something like the 200-500 sounds attractive.
Does it have to be a zoom, or would the 300mm PF work (lighter, maybe higher quality etc)?
Are you after maximum flexibility (so prepared to accept some compromises) or would you be prepared to lose a few chances in exchange for using a more restricted set of kit that gave you fewer but higher quality images?
Everything from landscapes, whales or bears from a little dingy to animal portraits in the zoo
I had the 200/2VR with the 1.7TC, a versatile and fast setup but not as versatile as a tele zoom. The 70-200 on DX was too short, the Sigma 120-300/2.8 worked better but the 200-400/4VR had a very usable range for my type of use combined with a D700 for low light (@ ISO4000 max) and a D300 for the range (@ ISO1600 max).
With smaller primes I rarely miss a moment, usually a step back or forth makes it work. With longer lenses you don't have that luxury, being able to quickly zoom out and shoot close by action is worth the loss in aperture speed IMHO.
Two simple examples where the 200-400 was set at 200mm to capture two images I would have hated to miss as they mark two memorable events (the reason why I started doing photography).
This male wanted to impress Chris Dees and me by getting within the 6 meter mark of my focus limiter
D700 & 200-400/4VR, Holland 2009This young elefant chased us around the block, I havent seen any images of the other participants in car with half a dozen photographers
D300 & 200-400/4VR, South Africa 2009