Anthony, Photo Ninja only outputs TIFFs or JPGs. But I'm comfortable converting and making global edits in a converter, then performing local edits on the TIFF in another. That method actually works well for my D810. Convert and adjust in View or PN, then do local edits on the TIFF in NX2 or PSE or Affinity (testing now).
For some that would be a choppy workflow. For me, it is OK because I do not have to do volume edits when pursuing artistic photography or when editing UV documentary photos (my other passion).
It has actually surprised me that for some photos quite often I do not need anything beyond Photo Ninja. And when I do, it is usually a need for cloning out dust bunnies and performing more localized sharpening.
Unfortunately I am beginning to lose my in-depth Photoshop skills now. I suppose if I needed to, I could brush up. I reserve the right to change my mind and plunge back into PS some day !!!! "-) "-) "-)