I have a MBP 15” 2016 with the latest OS and version of Lr & Ps CC Cloud and Classic: with the exception of some minor sync problems, everything runs fast and smoothly.
I finally upgraded to Mojave, MacOS 10.14.4, I have found no issues, and I specifically waited for the .4 update on my Macs to avoid some earlier bugs. I too use the latest Adobe Cloud versions of Ps & Lr, with no issues there either.
If anyone is having problems with the Adobe software I would not hesitate to call Adobe Support. They have always been very responsive when I've had troubles.
As long as we are talking Macs, users should be aware that we are getting very close to the point where Apple will stop supporting 32 bit software. Forewarned is forearmed.