I briefly handled both Tamron and Sigma 100-400 zooms at a shop and found that Tamron was more comfortable to operate thanks to its longer throw and smoother movement of the zoom ring.
However, if you already have another lens and dedicated accessories of Sigma, there could be no choice for Tamron. Sigma allows push-pull operation just like 150-600 "Sports" version, which can be handy, according to the usage.