BY default, the camera has long exposure noise reduction turned on which removes much of the noise. However, when photographing stars, you need to turn this off ( at least on my D300 ) or the NR will wipe out most of the stars as well as the noise.
The long exposure noise reduction is technically an automatic black frame subtraction. This is to compensate dark current related noise which may build up in long exposures. This built in 'long exposure noise reduction' is simple to use and sometimes convenient. It is also inconvenient as for each image it take a dead time while recording the black frame with same exposure time. I heard that with external timer exposing 10 minutes, it would be digesting for another 10 minutes with this setting. Astrophotographers often like to take black frames under their control and do black frame subtraction in post processing. The black frame subtraction definitely does not remove stars. However, the built in procedure multiplies noise by square root 2, which does not help faint stars. This limitation of black frame subtraction can be overcome by black frame stacking, which all needs to be done in post.
The D300 damages stars by its hot pixel suppression (HPS) algorithm which is on for 1/4s and longer exposures. Unfortunately, this feature cannot be turned off.
Recent Nikon cameras have improved a big lot in the low light area. Not only has the D7200 for example much less input referred read noise than D300 (see Bill Claff's web site) it also has higher quantum efficiency and also higher full well; there is now no objection against the new HPS which is well designe to distinguish hot pixels from star images.
Except, minor objection, it still cannot be turned off . Also the sensor is not much in need of dark current compensation, since dark current is so well controlled.